What exactly is Methyl Salicylate? |

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What exactly is Methyl Salicylate?

Therefore, What Exactly Is Methyl Salicylate? An In Depth In Accordance With Menthol

Methyl salicylate is just a natural ester that performs really similarly to menthol. It’s commonly removed through vapor distillation of wintergreen leaves.

In accordance with WebMD, methyl salicylate is situated in numerous topical ointments bought throughout the countertop for small joint aches or pains that are muscular. It could additionally be present in intimate services and products.

Therefore, what exactly is methyl salicylate and exactly what does it do? Both menthol and methyl salicylate are referred to as counterirritants, this means they cause cooling and sensations that are warming your skin. Counterirritants are primarily in charge of the title, and response, known as “icy hot.”

A lot of these services and products really should not be utilized on younger kids as a result of poisoning issues, which we’ll speak about later on in this essay.

Wintergreen Oil

You might remain wondering, what exactly is methyl salicylate? You will usually learn about wintergreen“oil or oil of wintergreen.” According to a summary in the Journal of Alternative Complementary Medicine, methyl salicylate may be thepredominant ingredient within the oil and is particularly the purest form in the Highest concentration you shall find. Based on an oil wintergreen podcast through the Royal Society of Chemistry, oil of wintergreen contains 96-99% methyl salicylate. Through the same supply, “…research indicates that give the combining form meaning sensitivity to pain. methyl salicylate is a component of the plant’s toolbox when you look at the battle against pathogens and herbivores.”

Methyl salicylate smells extremely highly of mint. Notwithstanding this, it must be noted that this ingredient will not belong when you look at the mint genus of plant species. The burning sensation that is cold activated through the TRPA1 channel. Methyl salicylate also activates the warmth channel TRPV1, that is similar channel considered to be activated by chilli peppers like capsaicin. Often, wintergreen oil can be used together with peppermint oil, considering that the two in tandem are considered to attenuate useful results. Wintergreen oil is acquired by vapor distillation associated with warmed, water-macerated leaves. It really is often utilized interchangeably with sweet birch oil for flavoring foods and candies.

Particular Products Which Utilize Methyl Salicylate

Based on drugs.com and goodguide.com, there are many products which contain methyl salicylate. Some items include…


Icy Hot Cream

Salonpas Soreness Patch

Analgesic Balm



Menthocin Patch with Lidocaine

Soothee Patch




CVS Mouth Rinse Natural Citrus

CVS Antiseptic Mouth Rinse

K-Y Yours+Mine Partners Lubricant

Jason Natural Cosmetics Dandruff Relief Treatment Shampoo

Forever Residing Aloe Heat Cream

Colgate Peroxyl Antiseptic Oral Cleanser, Original

Orajel PM Toothache cream

CVS Intensive Strength Toothache relief

Young thieves that are living Ultra Toothpaste

Eco-Dent Specialcare Toothpowders Tartarguard

Comparing Methyl Salicylate to Aspirin

One research posted in the Annals of Pharmacotherapy aimed to analyze the efficacy of methyl salicylate in platelet inhibition when comparing to aspirin. Platelet aggregation is yet another means of talking about platelets clumping together within the bloodstream. It is linked to blood clotting.

This research utilized a sample that is small of healthier guys into the 30-46 age groups. All participants got 162 mg of aspirin before a period that is washout then 5 g of 30% methyl preparation that is salicylate both to be used on the anterior legs. It absolutely was discovered that “both aspirin and MS produced statistically platelet that is significant; aspirin decreased the AUC from 183; 139 to 292 to 85; 48 to 128 (p = 0.008) and MS decreased the AUC from 197; 118 to 445 to 112; 88 to 306 (p = 0.011).”

There was clearly no big difference between the two. This implies that methyl salicylate works because effortlessly as aspirin for platelet aggregation, at minimum in healthy people.

Toxicity Fables and Concerns

Research with this substance on the net shall expose a number of instance reports of infant death. a things that are few be noted about these. Such infant fatalities often included the accidental swallowing of pure oil of wintergreen, the greatest concentration of methyl salicylate you will get.

This does not imply that overdoses can simply take place with ingestion; the substance could be consumed through your skin then incorporated into one’s system. But, it absolutely was present in “Toxicity fables: the particular danger of Gas Use,” published into the Global Journal of Aromatherapy, that, “if 10?ml of the 2.5% formula of wintergreen oil had been to be reproduced all at the same time to your epidermis and completely consumed, the dosage would express the exact same level of salicylate present in a single 325?mg aspirin tablet.”

This is the reason oil of wintergreen is regarded as to be reasonably low-risk with few effects that are side. Nevertheless, it is strongly suggested that brand new moms and dads avoid having the substance in the homely home, in the off-chance that a baby could easily get their or her arms onto it.

Additionally, it really is well worth noting that methyl salicylate happens to be restricted for usage in cosmetic makeup products in Canada.

Trace Quantities Are Contained In Hemp Seed Oil

Among numerous health great things about hemp seed oil constituents, you can find trace amounts of methyl salicylate. Hemp seed oil’s fatty acid content (omega-3s and omega-6s) is most remarkable being a health plus. The oil additionally contains 10-15% dietary fiber, 20-25% protein, and 20-30% carbs.

A bioassay posted in “The Composition of Hemp Seed Oil and its own Possibleas a source that is important of” reported from the methyl salicylate content of hemp seed oil. In addition they reported on the other side things contained in hemp seed oil, such as for instance cannabidiol, ?-Sitosterol, tocopherols, and terpenes and terpenoids.

To Conclude

So let’s review what we’ve learned therefore far:

Methyl salicylate is a normal ester that could be made naturally or synthetically into the lab it is often removed via vapor distillation of wintergreen leaves.

Oil of wintergreen may be the strongest, purest concentration of methyl salicylate.

TRY NOT TO INGEST oil of wintergreen.

Methyl salicylate can also be present in over-the-counter items such as for instance toothache ointments and muscle tissue pain relievers to alleviate discomfort and cause a soothing feeling. Additionally, it is sometimes utilized in a small amount to flavor foods and sweets.

Wintergreen oil put on skin in the doses that are right express the exact same number of salicylate present in one single 325 mg aspirin tablet.

Methyl salicylate works effortlessly against platelet aggregation—about as much as aspirin does.

Methyl salicylate can be found in hemp seed oil in trace quantities.